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A Novel Strategy to Regulate 1-Deoxynojirimycin Production Based on Its Biosynthetic Pathway in Streptomyces lavendulae

This study characterized the biosynthetic pathway of the secondary metabolite 1-deoxynojirimycin (DNJ) from Streptomyces lavendulae. The results revealed that glucose was a preferable precursor for DNJ synthesis, and its carbon skeleton underwent a C2-N-C6 cyclization reaction during synthesis. The...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Guo, Ye, Chen, Lei, Chen, Guiguang, Liang, Zhiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713920/
https://www.ncbi.nlm.nih.gov/pubmed/31507573
http://dx.doi.org/10.3389/fmicb.2019.01968