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A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

Genetic engineering is an important tool for redirecting the function of various types of immune cells and their use for therapeutic purpose. Although NK cells have many beneficial therapeutic features, genetic engineering of immune cells for targeted therapy focuses mostly on T cells. One of the ma...

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Detalles Bibliográficos
Autores principales: Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Schneider, Dina, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713925/
https://www.ncbi.nlm.nih.gov/pubmed/31507603
http://dx.doi.org/10.3389/fimmu.2019.02001