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Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure
Recent studies demonstrate that the stable HIV-1 reservoir in resting CD4(+) T cells is mostly formed from viruses circulating when combination antiretroviral therapy (ART) is initiated. Here we explore the immunological basis for these observations. Untreated HIV-1 infection is characterized by a p...
Autores principales: | Goonetilleke, Nilu, Clutton, Genevieve, Swanstrom, Ron, Joseph, Sarah B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714000/ https://www.ncbi.nlm.nih.gov/pubmed/31507594 http://dx.doi.org/10.3389/fimmu.2019.01966 |
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