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Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA(2))

Nicotinic acid (NA) activates hydroxycarboxylic acid receptor 2 (HCA(2)), and it is widely used in treating dyslipidaemias. Since its side effects include skin dryness, whereas its deficiency can be accompanied by dyssebacia, characterized by sebaceous gland enlargement, we asked if HCA(2) is expres...

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Detalles Bibliográficos
Autores principales: Markovics, Arnold, Tóth, Kinga Fanni, Sós, Katalin Eszter, Magi, József, Gyöngyösi, Adrienn, Benyó, Zoltán, Zouboulis, Christos C., Bíró, Tamás, Oláh, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714165/
https://www.ncbi.nlm.nih.gov/pubmed/31273921
http://dx.doi.org/10.1111/jcmm.14505