Local but not systemic administration of mesenchymal stromal cells ameliorates fibrogenesis in regenerating livers

Chronic liver injury leads to the accumulation of myofibroblasts resulting in increased collagen deposition and hepatic fibrogenesis. Treatments specifically targeting fibrogenesis are not yet available. Mesenchymal stromal cells (MSCs) are fibroblast‐like stromal (stem) cells, which stimulate tissu...

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Detalles Bibliográficos
Autores principales: van der Helm, Danny, Barnhoorn, Marieke C., de Jonge‐Muller, Eveline S. M., Molendijk, Ilse, Hawinkels, Luuk J. A. C., Coenraad, Minneke J., van Hoek, Bart, Verspaget, Hein W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714167/
https://www.ncbi.nlm.nih.gov/pubmed/31245923
http://dx.doi.org/10.1111/jcmm.14508

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