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Targeting the PI3K/STAT3 axis modulates age‐related differences in macrophage phenotype in rats with myocardial infarction

Ageing is associated with impaired repair mechanisms in cardiovascular diseases. Macrophages contribute to cardiac fibrosis after myocardial infarction (MI). The phosphatidyl‐inositol‐3‐kinase (PI3K) pathway has been shown to play a role in cardiac remodelling after MI. It remained unclear whether n...

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Detalles Bibliográficos
Autores principales: Lin, Chih‐Chan, Chen, Syue‐yi, Lien, Hsiao‐Yin, Lin, Shinn‐Zong, Lee, Tsung‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714172/
https://www.ncbi.nlm.nih.gov/pubmed/31313516
http://dx.doi.org/10.1111/jcmm.14526