Functional study of a KCNH2 mutant: Novel insights on the pathogenesis of the LQT2 syndrome

The K(+) voltage‐gated channel subfamily H member 2 (KCNH2) transports the rapid component of the cardiac delayed rectifying K(+) current. The aim of this study was to characterize the biophysical properties of a C‐terminus‐truncated KCNH2 channel, G1006fs/49 causing long QT syndrome type II in hete...

Descripción completa

Detalles Bibliográficos
Autores principales: De Zio, Roberta, Gerbino, Andrea, Forleo, Cinzia, Pepe, Martino, Milano, Serena, Favale, Stefano, Procino, Giuseppe, Svelto, Maria, Carmosino, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714209/
https://www.ncbi.nlm.nih.gov/pubmed/31361068
http://dx.doi.org/10.1111/jcmm.14521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714209/
https://www.ncbi.nlm.nih.gov/pubmed/31361068
http://dx.doi.org/10.1111/jcmm.14521

Ejemplares similares