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Functional study of a KCNH2 mutant: Novel insights on the pathogenesis of the LQT2 syndrome

The K(+) voltage‐gated channel subfamily H member 2 (KCNH2) transports the rapid component of the cardiac delayed rectifying K(+) current. The aim of this study was to characterize the biophysical properties of a C‐terminus‐truncated KCNH2 channel, G1006fs/49 causing long QT syndrome type II in hete...

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Detalles Bibliográficos
Autores principales:	De Zio, Roberta, Gerbino, Andrea, Forleo, Cinzia, Pepe, Martino, Milano, Serena, Favale, Stefano, Procino, Giuseppe, Svelto, Maria, Carmosino, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714209/ https://www.ncbi.nlm.nih.gov/pubmed/31361068 http://dx.doi.org/10.1111/jcmm.14521

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