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Down‐regulation of insulin‐like growth factor binding protein 5 is involved in intervertebral disc degeneration via the ERK signalling pathway

It is obvious that epigenetic processes influence the evolution of intervertebral disc degeneration (IDD). However, its molecular mechanisms are poorly understood. Therefore, we tested the hypothesis that IGFBP5, a potential regulator of IDD, modulates IDD via the ERK signalling pathway. We showed t...

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Detalles Bibliográficos
Autores principales: Chen, Zhonghui, Zhang, Weibing, Zhang, Nu, Zhou, Yan, Hu, Geliang, Xue, Mingdi, Liu, Junhua, Li, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714225/
https://www.ncbi.nlm.nih.gov/pubmed/31290273
http://dx.doi.org/10.1111/jcmm.14525