Cargando…
HBx combined with AFB1 triggers hepatic steatosis via COX‐2‐mediated necrosome formation and mitochondrial dynamics disorder
Hepatitis B virus (HBV) infection and aflatoxin B1 (AFB1) exposure have been recognized as independent risk factors for the occurrence and exacerbation of hepatic steatosis but their combined impacts and the potential mechanisms remain to be further elucidated. Here, we showed that exposure to AFB1...
Autores principales: | Chen, Yuan‐Yuan, Lin, Yi, Han, Pei‐Yu, Jiang, Shan, Che, Lin, He, Cheng‐Yong, Lin, Yu‐Chun, Lin, Zhong‐Ning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714226/ https://www.ncbi.nlm.nih.gov/pubmed/31282064 http://dx.doi.org/10.1111/jcmm.14388 |
Ejemplares similares
-
An outline of necrosome triggers
por: Vanden Berghe, Tom, et al.
Publicado: (2016) -
Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
por: Weber, Kathrin, et al.
Publicado: (2018) -
Intracellular antibody targeting HBx suppresses invasion and metastasis in hepatitis B virus‐related hepatocarcinogenesis via protein phosphatase 2A‐B56γ‐mediated dephosphorylation of protein kinase B
por: Che, Lin, et al.
Publicado: (2022) -
RIP3 is an upregulator of aerobic metabolism and the enhanced respiration by necrosomal RIP3 feeds back on necrosome to promote necroptosis
por: Qiu, Xingfeng, et al.
Publicado: (2018) -
BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming
por: Chen, Yuan-Yuan, et al.
Publicado: (2020)