Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme

BACKGROUND: Accumulating evidence demonstrates the oncogenic roles of lncRNA (long non-coding RNA) molecules in a wide variety of cancer types including glioma. Equally important, However, tumorigenic functions of lncRNA in glioma remain largely unclear. A recent study suggested lncRNA SNHG15 played...

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Detalles Bibliográficos
Autores principales: Li, Zhenzhe, Zhang, Jixing, Zheng, Hongshan, Li, Chenlong, Xiong, Jinsheng, Wang, Weiliang, Bao, Hongbo, Jin, Hua, Liang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714301/
https://www.ncbi.nlm.nih.gov/pubmed/31462285
http://dx.doi.org/10.1186/s13046-019-1371-0

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