High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting

BACKGROUND: The most common sex chromosomal aneuploidy in males is Klinefelter syndrome, which is characterized by at least one supernumerary X chromosome. While these men have long been considered infertile, focal spermatogenesis can be observed in some patients, and sperm can be surgically retriev...

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Detalles Bibliográficos
Autores principales: Laurentino, Sandra, Heckmann, Laura, Di Persio, Sara, Li, Xiaolin, Meyer zu Hörste, Gerd, Wistuba, Joachim, Cremers, Jann-Frederik, Gromoll, Jörg, Kliesch, Sabine, Schlatt, Stefan, Neuhaus, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714305/
https://www.ncbi.nlm.nih.gov/pubmed/31462300
http://dx.doi.org/10.1186/s13148-019-0720-3

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