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Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells

Diabetes is a metabolic disease, partly due to hypoinsulinism, which affects ∼8% of the world's adult population. Glibenclamide is known to promote insulin secretion by targeting β cells. Autophagy as a self-protective mechanism of cells has been widely studied and has particular physiological...

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Detalles Bibliográficos
Autores principales: Zhou, Jiali, Kang, Xincong, Luo, Yushuang, Yuan, Yuju, Wu, Yanyang, Wang, Meijun, Liu, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714319/
https://www.ncbi.nlm.nih.gov/pubmed/31511772
http://dx.doi.org/10.1155/2019/1265175