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Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells
Diabetes is a metabolic disease, partly due to hypoinsulinism, which affects ∼8% of the world's adult population. Glibenclamide is known to promote insulin secretion by targeting β cells. Autophagy as a self-protective mechanism of cells has been widely studied and has particular physiological...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714319/ https://www.ncbi.nlm.nih.gov/pubmed/31511772 http://dx.doi.org/10.1155/2019/1265175 |