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Ketamine Administration Reverses Corticosterone-Induced Alterations in Excitatory and Inhibitory Transmission in the Rat Dorsal Raphe Nucleus

Ketamine, a N-methyl-D-aspartate (NMDA) receptor antagonist, exerts rapid antidepressant effects in human patients and ameliorates depressive-like behavioral effects of chronic stress in animal models. Chronic stress and elevated corticosterone levels have been shown to modify serotonin (5-HT) neuro...

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Detalles Bibliográficos
Autores principales: Sowa, Joanna, Kusek, Magdalena, Bobula, Bartosz, Hess, Grzegorz, Tokarski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714325/
https://www.ncbi.nlm.nih.gov/pubmed/31511771
http://dx.doi.org/10.1155/2019/3219490