Cargando…

Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis

BACKGROUND: Structural variations such as copy number variations (CNVs) have a functional impact on various human traits. This study profiled genome-wide CNVs in Korean patients with rheumatoid arthritis (RA) to investigate the efficacy of treatment with TNF-α blockers. METHODS: A total of 357 Korea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Ki-Nam, Bang, So-Young, Lee, Hye-Soon, Park, Youngho, Kang, Ju-Yeon, Kim, Ji-Soong, Nam, Bora, Yoo, Hyun-Seung, Shin, Jung-Min, Lee, Yeon-Kyung, Lee, Tae-Han, Chun, Sehwan, Cho, Soo-Kyung, Choi, Chan-Bum, Sung, Yoon-Kyoung, Kim, Tae-Hwan, Jun, Jae-Bum, Yoo, Dae Hyun, Kim, Kwangwoo, Bae, Sang-Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714408/ https://www.ncbi.nlm.nih.gov/pubmed/31462329 http://dx.doi.org/10.1186/s13075-019-1983-y

Ejemplares similares

Drug retention and safety of TNF inhibitors in elderly patients with rheumatoid arthritis
por: Cho, Soo-Kyung, et al.
Publicado: (2016)

Fracture Risk and Its Prevention Patterns in Korean Patients with Polymyalgia Rheumatica: a Retrospective Cohort Study
por: Nam, Bora, et al.
Publicado: (2021)

Clinical and Genetic Risk Factors Associated With the Presence of Lupus Nephritis
por: Shin, Jung-Min, et al.
Publicado: (2021)

Genome-wide association study in a Korean population identifies six novel susceptibility loci for rheumatoid arthritis
por: Kwon, Young-Chang, et al.
Publicado: (2020)

Up-regulation of cyclooxygenase-2-derived prostaglandin E(2) in colon cancer cells resistant to 5-fluorouracil
por: Choi, Cheol Hee, et al.
Publicado: (2011)

Comparison of Two pMDIs in Adult Asthmatics: A Randomized Double-Blind Double-Dummy Clinical Trial
por: Nam, Tae-Hyun, et al.
Publicado: (2022)

Hyperkalemia from preoperative non-steroidal anti-inflammatory drugs and angiotensin II receptor blockers in patients with nephropathy
por: Song, Ho Kyung, et al.
Publicado: (2011)

Synthetic 3′,4′-Dihydroxyflavone Exerts Anti-Neuroinflammatory Effects in BV2 Microglia and a Mouse Model
por: Kim, Namkwon, et al.
Publicado: (2018)

MUC5B promoter variant rs35705950, rare but significant susceptibility locus in rheumatoid arthritis-interstitial lung disease with usual interstitial pneumonia in Asian populations
por: Joo, Young Bin, et al.
Publicado: (2022)

Long-Term Follow-Up Results From PET/CT Surveillance After Surgical Resection of Lung Adenocarcinoma Manifesting as Ground-Glass Opacity
por: Nam, Kyung Bum, et al.
Publicado: (2016)

Improved Sectional Image Analysis Technique for Evaluating Fiber Orientations in Fiber-Reinforced Cement-Based Materials
por: Lee, Bang Yeon, et al.
Publicado: (2016)

Imputing Variants in HLA-DR Beta Genes Reveals That HLA-DRB1 Is Solely Associated with Rheumatoid Arthritis and Systemic Lupus Erythematosus
por: Kim, Kwangwoo, et al.
Publicado: (2016)

Which is worse: uterine papillary serous carcinomas or carcinosarcomas?
por: Song, Taejong, et al.
Publicado: (2011)

Clinical and genetic factors associated with radiographic damage in patients with ankylosing spondylitis
por: Nam, Bora, et al.
Publicado: (2023)

Increased risk of herpes zoster with tofacitinib treatment in Korean patients with rheumatoid arthritis: a single-center prospective study
por: Song, Yeo-Jin, et al.
Publicado: (2023)

Prevalence and possible causes of hypouricemia at a tertiary care hospital
por: Son, Chang-Nam, et al.
Publicado: (2016)

The Effect of TNF-α Blocker HL036337 and Its Best Concentration to Inhibit Dry Eye Inflammation
por: Choi, Wungrak, et al.
Publicado: (2016)

The effect of propofol and sevoflurane on cancer cell, natural killer cell, and cytotoxic T lymphocyte function in patients undergoing breast cancer surgery: an in vitro analysis
por: Lim, Jeong-Ae, et al.
Publicado: (2018)

Risk factors for herpes zoster in Korean patients with rheumatoid arthritis treated with JAK inhibitor: a nested case–control study
por: Song, Yeo-Jin, et al.
Publicado: (2022)

Factors associated with selection of targeted therapy in patients with rheumatoid arthritis
por: Song, Yeo-Jin, et al.
Publicado: (2023)

A case report of motesanib-induced biliary sludge formation causing obstructive cholangitis with acute pancreatitis treated by endoscopic sphincterotomy
por: Song, Jay, et al.
Publicado: (2016)

Follow-up Testing of Interferon-Gamma Release Assays Are Useful in Ankylosing Spondylitis Patients Receiving Anti-Tumor Necrosis Factor Alpha for Latent Tuberculosis Infection
por: Son, Chang-Nam, et al.
Publicado: (2014)

Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms
por: Kim, Yeon Joo, et al.
Publicado: (2020)

Hypervalent iodine-mediated Ritter-type amidation of terminal alkenes: The synthesis of isoxazoline and pyrazoline cores
por: Park, Sang Won, et al.
Publicado: (2018)

Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program
por: Yoo, Tae Kyung, et al.
Publicado: (2023)

Early Experience With a Thermo-Expandable Stent (Memokath) for the Management of Recurrent Urethral Stricture
por: Jung, Hyun Su, et al.
Publicado: (2013)

Pain related to robotic cholecystectomy with lower abdominal ports: effect of the bilateral ultrasound-guided split injection technique of rectus sheath block in female patients: A prospective randomised trial
por: Kim, Jin Soo, et al.
Publicado: (2016)

Analysis of predictability of F‐18 fluorodeoxyglucose‐PET/CT in the recurrence of papillary thyroid carcinoma
por: Kim, Suk Kyeong, et al.
Publicado: (2016)

Identification of miR-143-3p as a diagnostic biomarker in gastric cancer
por: Ju, Yeongdon, et al.
Publicado: (2023)

Full thickness macular hole formation and spontaneous closure associated with branch retinal vein occlusion in a vitrectomized eye: A case report
por: Nam, Ki Yup, et al.
Publicado: (2020)

Association between N-Terminal Prohormone Brain Natriuretic Peptide and Decreased Skeletal Muscle Mass in a Healthy Adult Population: A Cross-Sectional Study
por: Yoo, Tae Kyung, et al.
Publicado: (2023)

Association-heterogeneity mapping identifies an Asian-specific association of the GTF2I locus with rheumatoid arthritis
por: Kim, Kwangwoo, et al.
Publicado: (2016)

Worse outcome of debridement, antibiotics, and implant retention in acute hematogenous infections than in postsurgical infections after total knee arthroplasty: a multicenter study
por: Chang, Moon Jong, et al.
Publicado: (2022)

Metformin Down-regulates TNF-α Secretion via Suppression of Scavenger Receptors in Macrophages
por: Hyun, Bobae, et al.
Publicado: (2013)

Increased Expression of Thymosin β(4) Is Independently Correlated with Hypoxia Inducible Factor-1α (HIF-1α) and Worse Clinical Outcome in Human Colorectal Cancer
por: Lee, Seung Yun, et al.
Publicado: (2017)

The effects of oligomeric proanthocyanidins on hydroxychloroquine-induced retinopathy as revealed by nationwide medical claim data for South Korea
por: Kim, Soyeon, et al.
Publicado: (2023)

Risk factors of asthma exacerbation based on asthma severity: a nationwide population-based observational study in South Korea
por: Kang, Hye-Rim, et al.
Publicado: (2018)

The frequency of and risk factors for osteoporosis in Korean patients with rheumatoid arthritis
por: Lee, Joo-Hyun, et al.
Publicado: (2016)

AB143. Relationship between post-voided dribbling & erectile dysfunction in men with lower urinary tract symptoms
por: Yang, Dae Yul, et al.
Publicado: (2015)

Neonatal diffusion tensor brain imaging predicts later motor outcome in preterm neonates with white matter abnormalities
por: Kim, Do-yeon, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e1b47rsc1eq6msu829gakfil1o