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Best practices for bioinformatic characterization of neoantigens for clinical utility
Neoantigens are newly formed peptides created from somatic mutations that are capable of inducing tumor-specific T cell recognition. Recently, researchers and clinicians have leveraged next generation sequencing technologies to identify neoantigens and to create personalized immunotherapies for canc...
Autores principales: | Richters, Megan M., Xia, Huiming, Campbell, Katie M., Gillanders, William E., Griffith, Obi L., Griffith, Malachi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714459/ https://www.ncbi.nlm.nih.gov/pubmed/31462330 http://dx.doi.org/10.1186/s13073-019-0666-2 |
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