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Ti-Catalyzed Cross-Cyclomagnesiation of 1,2-Dienes in the Total Z,Z,Z-Stereoselective Synthesis of Natural Acetogenin–Chatenaytrienin-1

[Image: see text] The first total synthesis of natural acetogenin, chatenaytrienin-1, was performed in 10 steps and in 41% overall yield using cross-cyclomagnesiation of (6Z)-heptadeca-1,2,6-triene and trideca-11,12-dien-1-ol tetrahydropyran acetal with EtMgBr in the presence of Mg metal and the Cp(...

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Detalles Bibliográficos
Autores principales:	D’yakonov, Vladimir A., Tuktarova, Regina A., Dzhemilev, Usein M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714518/ https://www.ncbi.nlm.nih.gov/pubmed/31497727 http://dx.doi.org/10.1021/acsomega.9b01951

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