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Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood–brain barrier model
BACKGROUND: Human induced pluripotent stem cells (hiPSC) hold great promise for use in cell therapy applications and for improved in vitro models of human disease. So far, most hiPSC differentiation protocols to astroglia use undefined, animal-containing culture matrices. Laminins, which play an ess...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714544/ https://www.ncbi.nlm.nih.gov/pubmed/31462266 http://dx.doi.org/10.1186/s12987-019-0147-4 |