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Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood–brain barrier model

BACKGROUND: Human induced pluripotent stem cells (hiPSC) hold great promise for use in cell therapy applications and for improved in vitro models of human disease. So far, most hiPSC differentiation protocols to astroglia use undefined, animal-containing culture matrices. Laminins, which play an ess...

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Detalles Bibliográficos
Autores principales:	Delsing, Louise, Kallur, Therése, Zetterberg, Henrik, Hicks, Ryan, Synnergren, Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714544/ https://www.ncbi.nlm.nih.gov/pubmed/31462266 http://dx.doi.org/10.1186/s12987-019-0147-4

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