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Pharmacological Differentiation of Thrombomodulin Alfa and Activated Protein C on Coagulation and Fibrinolysis In Vitro

Although thrombomodulin alfa (TM alfa), recombinant human soluble thrombomodulin, exerts antithrombogenic effects through activated protein C (APC), clinical trials suggested that TM alfa has a lower bleeding risk than does recombinant human APC. To address the mechanism explaining this difference,...

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Detalles Bibliográficos
Autores principales:	Tanaka, Kosuke, Tawara, Shunsuke, Tsuruta, Kazuhisa, Hoppensteadt, Debra, Fareed, Jawed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714727/ https://www.ncbi.nlm.nih.gov/pubmed/29683037 http://dx.doi.org/10.1177/1076029618770274

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