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Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With Single-Level Lumbar Fusion: A Prospective Study of 710 Cases
Lower limb deep vein thrombosis (DVT) is not an uncommon postoperative complication of spinal fusion surgery. However, the related risk factors identified in previous studies remain controversial. This study aimed to investigate risk factors for lower limb DVT in patients with single-level lumbar fu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714819/ https://www.ncbi.nlm.nih.gov/pubmed/30200770 http://dx.doi.org/10.1177/1076029618798940 |
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author | Zhao, Chun-Ming Zhang, Yu Yang, Si-Dong Huang, Ai-Bing Liang, Zong-Min Wu, Jian Chen, Qian |
author_facet | Zhao, Chun-Ming Zhang, Yu Yang, Si-Dong Huang, Ai-Bing Liang, Zong-Min Wu, Jian Chen, Qian |
author_sort | Zhao, Chun-Ming |
collection | PubMed |
description | Lower limb deep vein thrombosis (DVT) is not an uncommon postoperative complication of spinal fusion surgery. However, the related risk factors identified in previous studies remain controversial. This study aimed to investigate risk factors for lower limb DVT in patients with single-level lumbar fusion surgery. Between January 2010 and December 2016, a total of 710 patients undergoing lumbar fusion were recruited for this study, including 172 males and 538 females (aged 18-75 years). Deep vein thrombosis was detected by ultrasonography. Accordingly, patients were divided into the DVT group and the non-DVT group and compared in terms of operative data, underlying diseases, and biochemical data. Additionally, logistic regression analysis was performed to identify risk factors for lower limb DVT. The incidence of lower limb DVT was 11.8% (84 of 710 cases). Five patients were symptomatic, with lower limb pain and swelling. Two patients developed pulmonary embolism and 1 died. Binary logistic regression indicated that advanced age (P = .001, odds ratio [OR] = 2.86, 95% CI: 1.85-5.12), hypertension (P = .006, OR = 4.10, 95% CI: 1.09-2.30), and increased d-dimer (P < .001, OR = 3.49, 95% CI: 2.05-6.36) were risk factors for postoperative DVT. In conclusion, for patients with single-level lumbar fusion, advanced age, increased d-dimer, and hypertension may contribute to DVT development after spinal fusion surgery. Therefore, patients with these risk factors should be protected during the perioperative period. |
format | Online Article Text |
id | pubmed-6714819 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-67148192019-09-04 Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With Single-Level Lumbar Fusion: A Prospective Study of 710 Cases Zhao, Chun-Ming Zhang, Yu Yang, Si-Dong Huang, Ai-Bing Liang, Zong-Min Wu, Jian Chen, Qian Clin Appl Thromb Hemost Original Articles Lower limb deep vein thrombosis (DVT) is not an uncommon postoperative complication of spinal fusion surgery. However, the related risk factors identified in previous studies remain controversial. This study aimed to investigate risk factors for lower limb DVT in patients with single-level lumbar fusion surgery. Between January 2010 and December 2016, a total of 710 patients undergoing lumbar fusion were recruited for this study, including 172 males and 538 females (aged 18-75 years). Deep vein thrombosis was detected by ultrasonography. Accordingly, patients were divided into the DVT group and the non-DVT group and compared in terms of operative data, underlying diseases, and biochemical data. Additionally, logistic regression analysis was performed to identify risk factors for lower limb DVT. The incidence of lower limb DVT was 11.8% (84 of 710 cases). Five patients were symptomatic, with lower limb pain and swelling. Two patients developed pulmonary embolism and 1 died. Binary logistic regression indicated that advanced age (P = .001, odds ratio [OR] = 2.86, 95% CI: 1.85-5.12), hypertension (P = .006, OR = 4.10, 95% CI: 1.09-2.30), and increased d-dimer (P < .001, OR = 3.49, 95% CI: 2.05-6.36) were risk factors for postoperative DVT. In conclusion, for patients with single-level lumbar fusion, advanced age, increased d-dimer, and hypertension may contribute to DVT development after spinal fusion surgery. Therefore, patients with these risk factors should be protected during the perioperative period. SAGE Publications 2018-09-10 2018-12 /pmc/articles/PMC6714819/ /pubmed/30200770 http://dx.doi.org/10.1177/1076029618798940 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Zhao, Chun-Ming Zhang, Yu Yang, Si-Dong Huang, Ai-Bing Liang, Zong-Min Wu, Jian Chen, Qian Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title | Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With
Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title_full | Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With
Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title_fullStr | Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With
Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title_full_unstemmed | Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With
Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title_short | Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With
Single-Level Lumbar Fusion: A Prospective Study of 710 Cases |
title_sort | risk factors for lower limb deep vein thrombosis in patients with
single-level lumbar fusion: a prospective study of 710 cases |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714819/ https://www.ncbi.nlm.nih.gov/pubmed/30200770 http://dx.doi.org/10.1177/1076029618798940 |
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