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Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a pro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714823/ https://www.ncbi.nlm.nih.gov/pubmed/30049232 http://dx.doi.org/10.1177/1076029618786577 |
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author | Bosevski, Marijan Krstevski, Gorjan Gjorgievski, Atanas Mitevska, Irena Kostovska, Elizabeta Srbinovska |
author_facet | Bosevski, Marijan Krstevski, Gorjan Gjorgievski, Atanas Mitevska, Irena Kostovska, Elizabeta Srbinovska |
author_sort | Bosevski, Marijan |
collection | PubMed |
description | The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a prospective study. Pulmonary embolism was confirmed by computed tomography angiography in all the patients, while deep venous thrombosis was confirmed by ultrasound in 21 patients. Study population was followed up for 6.7 months. Multivariate regression analysis was done where right ventricular (RV) diameter (mean 37.5 mm), systolic pulmonary artery pressure (68 ± 23 mm Hg) measured by echocardiography, d-dimer level at baseline 2654.5 ± 420.3 ng/mL, number of comorbidities (2.4 ± 0.7), and present symptoms (3.1 ± 0.9) entered the model. The model was age-adjusted. d-dimer level was revealed as a predictor for the length of hospitalization (β = .25, P = .05) and RV diameter as a factor for duration of anticoagulation (β = .29, P = .05). Our results imply that the baseline measurement of these parameters independently influence both the short-term and long-term prognosis of patients with nonfatal PE. |
format | Online Article Text |
id | pubmed-6714823 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-67148232019-09-04 Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study Bosevski, Marijan Krstevski, Gorjan Gjorgievski, Atanas Mitevska, Irena Kostovska, Elizabeta Srbinovska Clin Appl Thromb Hemost Original Articles The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a prospective study. Pulmonary embolism was confirmed by computed tomography angiography in all the patients, while deep venous thrombosis was confirmed by ultrasound in 21 patients. Study population was followed up for 6.7 months. Multivariate regression analysis was done where right ventricular (RV) diameter (mean 37.5 mm), systolic pulmonary artery pressure (68 ± 23 mm Hg) measured by echocardiography, d-dimer level at baseline 2654.5 ± 420.3 ng/mL, number of comorbidities (2.4 ± 0.7), and present symptoms (3.1 ± 0.9) entered the model. The model was age-adjusted. d-dimer level was revealed as a predictor for the length of hospitalization (β = .25, P = .05) and RV diameter as a factor for duration of anticoagulation (β = .29, P = .05). Our results imply that the baseline measurement of these parameters independently influence both the short-term and long-term prognosis of patients with nonfatal PE. SAGE Publications 2018-07-26 2018-12 /pmc/articles/PMC6714823/ /pubmed/30049232 http://dx.doi.org/10.1177/1076029618786577 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Bosevski, Marijan Krstevski, Gorjan Gjorgievski, Atanas Mitevska, Irena Kostovska, Elizabeta Srbinovska Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study |
title | Predictors for Prognosis in Patients With Nonfatal Pulmonary
Embolism: A Registry-Based Cohort Study |
title_full | Predictors for Prognosis in Patients With Nonfatal Pulmonary
Embolism: A Registry-Based Cohort Study |
title_fullStr | Predictors for Prognosis in Patients With Nonfatal Pulmonary
Embolism: A Registry-Based Cohort Study |
title_full_unstemmed | Predictors for Prognosis in Patients With Nonfatal Pulmonary
Embolism: A Registry-Based Cohort Study |
title_short | Predictors for Prognosis in Patients With Nonfatal Pulmonary
Embolism: A Registry-Based Cohort Study |
title_sort | predictors for prognosis in patients with nonfatal pulmonary
embolism: a registry-based cohort study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714823/ https://www.ncbi.nlm.nih.gov/pubmed/30049232 http://dx.doi.org/10.1177/1076029618786577 |
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