Cargando…

Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study

The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Bosevski, Marijan, Krstevski, Gorjan, Gjorgievski, Atanas, Mitevska, Irena, Kostovska, Elizabeta Srbinovska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714823/
https://www.ncbi.nlm.nih.gov/pubmed/30049232
http://dx.doi.org/10.1177/1076029618786577
_version_ 1783447125656338432
author Bosevski, Marijan
Krstevski, Gorjan
Gjorgievski, Atanas
Mitevska, Irena
Kostovska, Elizabeta Srbinovska
author_facet Bosevski, Marijan
Krstevski, Gorjan
Gjorgievski, Atanas
Mitevska, Irena
Kostovska, Elizabeta Srbinovska
author_sort Bosevski, Marijan
collection PubMed
description The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a prospective study. Pulmonary embolism was confirmed by computed tomography angiography in all the patients, while deep venous thrombosis was confirmed by ultrasound in 21 patients. Study population was followed up for 6.7 months. Multivariate regression analysis was done where right ventricular (RV) diameter (mean 37.5 mm), systolic pulmonary artery pressure (68 ± 23 mm Hg) measured by echocardiography, d-dimer level at baseline 2654.5 ± 420.3 ng/mL, number of comorbidities (2.4 ± 0.7), and present symptoms (3.1 ± 0.9) entered the model. The model was age-adjusted. d-dimer level was revealed as a predictor for the length of hospitalization (β = .25, P = .05) and RV diameter as a factor for duration of anticoagulation (β = .29, P = .05). Our results imply that the baseline measurement of these parameters independently influence both the short-term and long-term prognosis of patients with nonfatal PE.
format Online
Article
Text
id pubmed-6714823
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-67148232019-09-04 Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study Bosevski, Marijan Krstevski, Gorjan Gjorgievski, Atanas Mitevska, Irena Kostovska, Elizabeta Srbinovska Clin Appl Thromb Hemost Original Articles The article’s aim was to determine predictors for short- and long-term prognosis of patients with pulmonary embolism (PE). Cohort prospective study based on the National registry on venous thromboembolism. Eighty-four patients with PE, on age 60.3 + 12.5 years, were selected and followed up in a prospective study. Pulmonary embolism was confirmed by computed tomography angiography in all the patients, while deep venous thrombosis was confirmed by ultrasound in 21 patients. Study population was followed up for 6.7 months. Multivariate regression analysis was done where right ventricular (RV) diameter (mean 37.5 mm), systolic pulmonary artery pressure (68 ± 23 mm Hg) measured by echocardiography, d-dimer level at baseline 2654.5 ± 420.3 ng/mL, number of comorbidities (2.4 ± 0.7), and present symptoms (3.1 ± 0.9) entered the model. The model was age-adjusted. d-dimer level was revealed as a predictor for the length of hospitalization (β = .25, P = .05) and RV diameter as a factor for duration of anticoagulation (β = .29, P = .05). Our results imply that the baseline measurement of these parameters independently influence both the short-term and long-term prognosis of patients with nonfatal PE. SAGE Publications 2018-07-26 2018-12 /pmc/articles/PMC6714823/ /pubmed/30049232 http://dx.doi.org/10.1177/1076029618786577 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Bosevski, Marijan
Krstevski, Gorjan
Gjorgievski, Atanas
Mitevska, Irena
Kostovska, Elizabeta Srbinovska
Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title_full Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title_fullStr Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title_full_unstemmed Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title_short Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study
title_sort predictors for prognosis in patients with nonfatal pulmonary embolism: a registry-based cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714823/
https://www.ncbi.nlm.nih.gov/pubmed/30049232
http://dx.doi.org/10.1177/1076029618786577
work_keys_str_mv AT bosevskimarijan predictorsforprognosisinpatientswithnonfatalpulmonaryembolismaregistrybasedcohortstudy
AT krstevskigorjan predictorsforprognosisinpatientswithnonfatalpulmonaryembolismaregistrybasedcohortstudy
AT gjorgievskiatanas predictorsforprognosisinpatientswithnonfatalpulmonaryembolismaregistrybasedcohortstudy
AT mitevskairena predictorsforprognosisinpatientswithnonfatalpulmonaryembolismaregistrybasedcohortstudy
AT kostovskaelizabetasrbinovska predictorsforprognosisinpatientswithnonfatalpulmonaryembolismaregistrybasedcohortstudy