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Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures

This study aimed to investigate the incidence and risk factors for deep vein thrombosis (DVT) in patients with pelvic and acetabular fractures. Patients with pelvic or acetabular fractures were included. Demographic data, fracture classification, time to surgery, and d-dimer levels at admission and...

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Autores principales: Wang, Pengfei, Kandemir, Utku, Zhang, Binfei, Wang, Baohui, Li, Jiahao, Zhuang, Yan, Wang, Hu, Zhang, Hong, Liu, Ping, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714909/
https://www.ncbi.nlm.nih.gov/pubmed/31014089
http://dx.doi.org/10.1177/1076029619845066
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author Wang, Pengfei
Kandemir, Utku
Zhang, Binfei
Wang, Baohui
Li, Jiahao
Zhuang, Yan
Wang, Hu
Zhang, Hong
Liu, Ping
Zhang, Kun
author_facet Wang, Pengfei
Kandemir, Utku
Zhang, Binfei
Wang, Baohui
Li, Jiahao
Zhuang, Yan
Wang, Hu
Zhang, Hong
Liu, Ping
Zhang, Kun
author_sort Wang, Pengfei
collection PubMed
description This study aimed to investigate the incidence and risk factors for deep vein thrombosis (DVT) in patients with pelvic and acetabular fractures. Patients with pelvic or acetabular fractures were included. Demographic data, fracture classification, time to surgery, and d-dimer levels at admission and one day after surgical intervention were recorded. Duplex ultrasonography was performed in the lower extremities for DVT evaluation. All patients received mechanical and chemical thromboprophylaxis. One hundred ten patients with a mean age of 44.2 ± 13.8 years were included. There were 48 patients with pelvic fractures and 62 patients with acetabular fractures. Thirty-two (29.09%) patients sustained DVT; 21 (19.09%) patients exhibited proximal thrombosis, and 3 patients suffered pulmonary embolism. The incidence of DVT in patients with acetabular fractures was significantly higher than that of patients with pelvic fractures (χ(2) = 4.42, P = .04). The incidence of proximal DVT was significantly higher in patients with complex acetabular fractures than in patients with simple acetabular fractures (χ(2) = 6.65, P = .01). Multivariate analysis showed that age older than 60 years, associated injuries, and the time to surgery longer than 2 weeks were independent risk factors (P < .05). Despite mechanical and chemical thromboprophylaxis, the risk of DVT in patients with pelvic and acetabular fractures is still very high, and most of the thromboses were localized proximally. The risk of DVT is higher in patients older than 60 years, in those with associated injuries, and when the time from injury to operation is more than 2 weeks.
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spelling pubmed-67149092019-09-04 Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures Wang, Pengfei Kandemir, Utku Zhang, Binfei Wang, Baohui Li, Jiahao Zhuang, Yan Wang, Hu Zhang, Hong Liu, Ping Zhang, Kun Clin Appl Thromb Hemost Original Article This study aimed to investigate the incidence and risk factors for deep vein thrombosis (DVT) in patients with pelvic and acetabular fractures. Patients with pelvic or acetabular fractures were included. Demographic data, fracture classification, time to surgery, and d-dimer levels at admission and one day after surgical intervention were recorded. Duplex ultrasonography was performed in the lower extremities for DVT evaluation. All patients received mechanical and chemical thromboprophylaxis. One hundred ten patients with a mean age of 44.2 ± 13.8 years were included. There were 48 patients with pelvic fractures and 62 patients with acetabular fractures. Thirty-two (29.09%) patients sustained DVT; 21 (19.09%) patients exhibited proximal thrombosis, and 3 patients suffered pulmonary embolism. The incidence of DVT in patients with acetabular fractures was significantly higher than that of patients with pelvic fractures (χ(2) = 4.42, P = .04). The incidence of proximal DVT was significantly higher in patients with complex acetabular fractures than in patients with simple acetabular fractures (χ(2) = 6.65, P = .01). Multivariate analysis showed that age older than 60 years, associated injuries, and the time to surgery longer than 2 weeks were independent risk factors (P < .05). Despite mechanical and chemical thromboprophylaxis, the risk of DVT in patients with pelvic and acetabular fractures is still very high, and most of the thromboses were localized proximally. The risk of DVT is higher in patients older than 60 years, in those with associated injuries, and when the time from injury to operation is more than 2 weeks. SAGE Publications 2019-04-24 /pmc/articles/PMC6714909/ /pubmed/31014089 http://dx.doi.org/10.1177/1076029619845066 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Wang, Pengfei
Kandemir, Utku
Zhang, Binfei
Wang, Baohui
Li, Jiahao
Zhuang, Yan
Wang, Hu
Zhang, Hong
Liu, Ping
Zhang, Kun
Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title_full Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title_fullStr Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title_full_unstemmed Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title_short Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures
title_sort incidence and risk factors of deep vein thrombosis in patients with pelvic and acetabular fractures
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714909/
https://www.ncbi.nlm.nih.gov/pubmed/31014089
http://dx.doi.org/10.1177/1076029619845066
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