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Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum
The currently available oral anti-Xa agents are claimed to produce their anticoagulant and antithrombotic effects solely by the inhibition of factor Xa. This study profiled various anti-Xa drugs in routinely used laboratory assays to demonstrate that their effects are not solely related to the anti-...
Autores principales: | Siddiqui, Fakiha, Hoppensteadt, Debra, Jeske, Walter, Iqbal, Omer, Tafur, Alfonso, Fareed, Jawed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714936/ https://www.ncbi.nlm.nih.gov/pubmed/31088146 http://dx.doi.org/10.1177/1076029619847524 |
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