The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection

The causative mutation responsible for limb girdle muscular dystrophy 1F (LGMD1F) is one heterozygous single nucleotide deletion in the stop codon of the nuclear import factor Transportin 3 gene (TNPO3). This mutation causes a carboxy-terminal extension of 15 amino acids, producing a protein of unkn...

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Detalles Bibliográficos
Autores principales: Rodríguez-Mora, Sara, De Wit, Flore, García-Perez, Javier, Bermejo, Mercedes, López-Huertas, María Rosa, Mateos, Elena, Martí, Pilar, Rocha, Susana, Vigón, Lorena, Christ, Frauke, Debyser, Zeger, Vílchez, Juan Jesús, Coiras, Mayte, Alcamí, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715175/
https://www.ncbi.nlm.nih.gov/pubmed/31465518
http://dx.doi.org/10.1371/journal.ppat.1007958

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