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TeXP: Deconvolving the effects of pervasive and autonomous transcription of transposable elements

The Long interspersed nuclear element 1 (LINE-1) is a primary source of genetic variation in humans and other mammals. Despite its importance, LINE-1 activity remains difficult to study because of its highly repetitive nature. Here, we developed and validated a method called TeXP to gauge LINE-1 act...

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Detalles Bibliográficos
Autores principales: Navarro, Fabio CP, Hoops, Jacob, Bellfy, Lauren, Cerveira, Eliza, Zhu, Qihui, Zhang, Chengsheng, Lee, Charles, Gerstein, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715295/
https://www.ncbi.nlm.nih.gov/pubmed/31425522
http://dx.doi.org/10.1371/journal.pcbi.1007293