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PP1 and PP2A Use Opposite Phospho-dependencies to Control Distinct Processes at the Kinetochore
PP1 and PP2A-B56 are major serine/threonine phosphatase families that achieve specificity by colocalizing with substrates. At the kinetochore, however, both phosphatases localize to an almost identical molecular space and yet they still manage to regulate unique pathways and processes. By switching...
Autores principales: | Smith, Richard J., Cordeiro, Marilia H., Davey, Norman E., Vallardi, Giulia, Ciliberto, Andrea, Gross, Fridolin, Saurin, Adrian T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715587/ https://www.ncbi.nlm.nih.gov/pubmed/31433993 http://dx.doi.org/10.1016/j.celrep.2019.07.067 |
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