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Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome
Proteasomes are a critical component of quality control that regulate turnover of short-lived, unfolded, and misfolded proteins. Proteasome activity has been therapeutically targeted and considered as a treatment option for several chronic lung disorders including pulmonary fibrosis. Although pharma...
Autores principales: | Sitaraman, Sneha, Na, Cheng-Lun, Yang, Li, Filuta, Alyssa, Bridges, James P., Weaver, Timothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715642/ https://www.ncbi.nlm.nih.gov/pubmed/31467330 http://dx.doi.org/10.1038/s41598-019-49020-4 |
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