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Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome

Proteasomes are a critical component of quality control that regulate turnover of short-lived, unfolded, and misfolded proteins. Proteasome activity has been therapeutically targeted and considered as a treatment option for several chronic lung disorders including pulmonary fibrosis. Although pharma...

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Detalles Bibliográficos
Autores principales: Sitaraman, Sneha, Na, Cheng-Lun, Yang, Li, Filuta, Alyssa, Bridges, James P., Weaver, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715642/
https://www.ncbi.nlm.nih.gov/pubmed/31467330
http://dx.doi.org/10.1038/s41598-019-49020-4

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