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DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use
The risk of gastric cancer (GC) declines after Helicobacter pylori (H. pylori) eradication and long-term aspirin use. We evaluated the effects of H. pylori eradication (Cohort 1) and aspirin use (Cohort 2) on the methylation of microRNAs (miRNAs), such as miR-34c, miR-124a-3, miR-129-2, and miR-137,...
Autores principales: | Watari, Jiro, Ito, Chiyomi, Shimoda, Tadakazu, Tomita, Toshihiko, Oshima, Tadayuki, Fukui, Hirokazu, Das, Kiron M., Miwa, Hiroto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715663/ https://www.ncbi.nlm.nih.gov/pubmed/31467363 http://dx.doi.org/10.1038/s41598-019-49069-1 |
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