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Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination
Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system, and have the capacity to regenerate oligodendrocytes and myelin. However, in inflammatory diseases such as multiple sclerosis (MS) remyelination is often incomplete. To investigate how neuroinflammation influenc...
Autores principales: | Kirby, Leslie, Jin, Jing, Cardona, Jaime Gonzalez, Smith, Matthew D., Martin, Kyle A., Wang, Jingya, Strasburger, Hayley, Herbst, Leyla, Alexis, Maya, Karnell, Jodi, Davidson, Todd, Dutta, Ranjan, Goverman, Joan, Bergles, Dwight, Calabresi, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715717/ https://www.ncbi.nlm.nih.gov/pubmed/31467299 http://dx.doi.org/10.1038/s41467-019-11638-3 |
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