Changes in gene expression predictably shift and switch genetic interactions

Non-additive interactions between mutations occur extensively and also change across conditions, making genetic prediction a difficult challenge. To better understand the plasticity of genetic interactions (epistasis), we combine mutations in a single protein performing a single function (a transcri...

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Detalles Bibliográficos
Autores principales: Li, Xianghua, Lalić, Jasna, Baeza-Centurion, Pablo, Dhar, Riddhiman, Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715729/
https://www.ncbi.nlm.nih.gov/pubmed/31467279
http://dx.doi.org/10.1038/s41467-019-11735-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715729/
https://www.ncbi.nlm.nih.gov/pubmed/31467279
http://dx.doi.org/10.1038/s41467-019-11735-3

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