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Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

Abnormal regulation and expression of microRNAs (miRNAs) has been documented in various diseases including cancer. The miRNA let-7 (MIRLET7) family controls developmental timing and differentiation. Let-7 loss contributes to carcinogenesis via an increase in its target oncogenes and stemness factors...

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Detalles Bibliográficos
Autores principales: Chirshev, Evgeny, Oberg, Kerby C., Ioffe, Yevgeniya J., Unternaehrer, Juli J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715759/
https://www.ncbi.nlm.nih.gov/pubmed/31468250
http://dx.doi.org/10.1186/s40169-019-0240-y

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