Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar

FGF signaling plays a critical role in tooth development, and mutations in modulators of this pathway produce a number of striking phenotypes. However, many aspects of the role of the FGF pathway in regulating the morphological features and the mineral quality of the dentition remain unknown. Here,...

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Detalles Bibliográficos
Autores principales: Marangoni, Pauline, Charles, Cyril, Ahn, Youngwook, Seidel, Kerstin, Jheon, Andrew, Ganss, Bernhard, Krumlauf, Robb, Viriot, Laurent, Klein, Ophir D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715786/
https://www.ncbi.nlm.nih.gov/pubmed/31485553
http://dx.doi.org/10.1002/jbm4.10205

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