Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease

Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major contributor to the pathogenesis of neovascular AMD (nAMD). Intravitreal injections of anti-VEGF drugs have shown dramatic visual benefits for AMD...

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Detalles Bibliográficos
Autores principales: Matsuda, Yusaku, Nonaka, Yosuke, Futakawa, Satoshi, Imai, Hirotaka, Akita, Kazumasa, Nishihata, Toshiaki, Fujiwara, Masatoshi, Ali, Yusuf, Bhisitkul, Robert B., Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716068/
https://www.ncbi.nlm.nih.gov/pubmed/31454678
http://dx.doi.org/10.1016/j.omtn.2019.07.018

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