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Explicit Characterization of the Free Energy Landscape of pKID–KIX Coupled Folding and Binding

[Image: see text] The most fundamental aspect of the free energy landscape of proteins is that it is globally funneled such that protein folding is energetically biased. Then, what are the distinctive characteristics of the landscape of intrinsically disordered proteins, apparently lacking such ener...

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Detalles Bibliográficos
Autores principales: Chong, Song-Ho, Im, Haeri, Ham, Sihyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716127/
https://www.ncbi.nlm.nih.gov/pubmed/31482116
http://dx.doi.org/10.1021/acscentsci.9b00200