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Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction

[Image: see text] The zwitterionic Streptococcus pneumoniae serotype 1 polysaccharide (Sp1) is an important anchor point for our immune system to act against streptococcal infections. Antibodies can recognize Sp1 saccharides, and it has been postulated that Sp1 can elicit a T-cell-dependent immune r...

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Detalles Bibliográficos
Autores principales:	Zhang, Qingju, Gimeno, Ana, Santana, Darielys, Wang, Zhen, Valdés-Balbin, Yury, Rodríguez-Noda, Laura M., Hansen, Thomas, Kong, Li, Shen, Mengjie, Overkleeft, Herman S., Vérez-Bencomo, Vicente, van der Marel, Gijsbert A., Jiménez-Barbero, Jesús, Chiodo, Fabrizio, Codée, Jeroen D. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716135/ https://www.ncbi.nlm.nih.gov/pubmed/31482123 http://dx.doi.org/10.1021/acscentsci.9b00454

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