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Microglial Drug Targets in AD: Opportunities and Challenges in Drug Discovery and Development
Alzheimer’s disease (AD) is a large and increasing unmet medical need with no disease-modifying treatment currently available. Genetic evidence from genome-wide association studies (GWASs) and gene network analysis has clearly revealed a key role of the innate immune system in the brain, of which mi...
Autores principales: | Biber, Knut, Bhattacharya, Anindya, Campbell, Brian M., Piro, Justin R., Rohe, Michael, Staal, Roland G.W., Talanian, Robert V., Möller, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716448/ https://www.ncbi.nlm.nih.gov/pubmed/31507408 http://dx.doi.org/10.3389/fphar.2019.00840 |
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