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Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p

Long non-coding RNAs (lncRNAs) play pivotal roles in diseases such as osteoarthritis (OA). However, knowledge of the biological roles of lncRNAs is limited in OA. We aimed to explore the biological function and molecular mechanism of HOTTIP in chondrogenesis and cartilage degradation. We used the hu...

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Detalles Bibliográficos
Autores principales: Mao, Guping, Kang, Yan, Lin, Ruifu, Hu, Shu, Zhang, Ziji, Li, Hongyi, Liao, Weiming, Zhang, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716540/
https://www.ncbi.nlm.nih.gov/pubmed/31508417
http://dx.doi.org/10.3389/fcell.2019.00161