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Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors

To examine the characteristics and short-term outcome of perioperative myocardial infarction (PMI), a single-center retrospective study was carried out. The electronic medical records of 278,939 patients aged 45 years or older who underwent non-cardiac surgery at Renji Hospital from January 2003 to...

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Autores principales: Zhou, Xiaoxin, Chen, Lingke, Su, Zhongxue, Li, Yue, Tu, Mengyun, Xiao, Jie, Pan, Zhiying, Su, Diansan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716711/
https://www.ncbi.nlm.nih.gov/pubmed/31441880
http://dx.doi.org/10.1097/MD.0000000000016929
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author Zhou, Xiaoxin
Chen, Lingke
Su, Zhongxue
Li, Yue
Tu, Mengyun
Xiao, Jie
Pan, Zhiying
Su, Diansan
author_facet Zhou, Xiaoxin
Chen, Lingke
Su, Zhongxue
Li, Yue
Tu, Mengyun
Xiao, Jie
Pan, Zhiying
Su, Diansan
author_sort Zhou, Xiaoxin
collection PubMed
description To examine the characteristics and short-term outcome of perioperative myocardial infarction (PMI), a single-center retrospective study was carried out. The electronic medical records of 278,939 patients aged 45 years or older who underwent non-cardiac surgery at Renji Hospital from January 2003 to December 2015 were screened based on diagnostic codes (ICD121, ICD121.0, ICD121.1, ICD121.2, ICD121.3, ICD121.4, or ICD121.9). The incidence and characteristics of PMI and mortality risk factors were analyzed after non-cardiac surgery. PMI was reported in 45 patients, with an incidence rate of 1.61 per 10,000 and a mortality rate of 75.6% (34/45). The PMI incidence rate increased significantly with age. The PMI incidence rate was the highest for vascular surgery (5.82 per 10,000 cases). PMI occurs mainly within 48 h of surgery, with most cases showing an onset in the general wards. Logistic analysis showed that the use of nitrates is the independent protective factor for the outcomes of patients with PMI. The incidence of PMI in non-cardiac surgery is approximately 2 of 10,000 in patients aged 45 years or older, and increased significantly with age. The use of nitrates might be helpful for their survival.
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spelling pubmed-67167112019-10-01 Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors Zhou, Xiaoxin Chen, Lingke Su, Zhongxue Li, Yue Tu, Mengyun Xiao, Jie Pan, Zhiying Su, Diansan Medicine (Baltimore) 3300 To examine the characteristics and short-term outcome of perioperative myocardial infarction (PMI), a single-center retrospective study was carried out. The electronic medical records of 278,939 patients aged 45 years or older who underwent non-cardiac surgery at Renji Hospital from January 2003 to December 2015 were screened based on diagnostic codes (ICD121, ICD121.0, ICD121.1, ICD121.2, ICD121.3, ICD121.4, or ICD121.9). The incidence and characteristics of PMI and mortality risk factors were analyzed after non-cardiac surgery. PMI was reported in 45 patients, with an incidence rate of 1.61 per 10,000 and a mortality rate of 75.6% (34/45). The PMI incidence rate increased significantly with age. The PMI incidence rate was the highest for vascular surgery (5.82 per 10,000 cases). PMI occurs mainly within 48 h of surgery, with most cases showing an onset in the general wards. Logistic analysis showed that the use of nitrates is the independent protective factor for the outcomes of patients with PMI. The incidence of PMI in non-cardiac surgery is approximately 2 of 10,000 in patients aged 45 years or older, and increased significantly with age. The use of nitrates might be helpful for their survival. Wolters Kluwer Health 2019-08-23 /pmc/articles/PMC6716711/ /pubmed/31441880 http://dx.doi.org/10.1097/MD.0000000000016929 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 3300
Zhou, Xiaoxin
Chen, Lingke
Su, Zhongxue
Li, Yue
Tu, Mengyun
Xiao, Jie
Pan, Zhiying
Su, Diansan
Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title_full Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title_fullStr Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title_full_unstemmed Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title_short Perioperative acute myocardial infarction in patients after non-cardiac surgery in China: Characteristics and risk factors
title_sort perioperative acute myocardial infarction in patients after non-cardiac surgery in china: characteristics and risk factors
topic 3300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716711/
https://www.ncbi.nlm.nih.gov/pubmed/31441880
http://dx.doi.org/10.1097/MD.0000000000016929
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