Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a commonly used one-step modality for peritoneal surface malignancies. Despite the gain in popularity and effectiveness, HIPEC is still associated with significant post-operative morbidity and mortality. Liv...

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Detalles Bibliográficos
Autores principales: Kohli, Pavneet, Penumadu, Prasanth, Subramaniam., Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Anesthesiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716744/
https://www.ncbi.nlm.nih.gov/pubmed/31497453
http://dx.doi.org/10.7759/cureus.5026
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author Kohli, Pavneet
Penumadu, Prasanth
Subramaniam., Rajkumar
author_facet Kohli, Pavneet
Penumadu, Prasanth
Subramaniam., Rajkumar
author_sort Kohli, Pavneet
collection PubMed
description Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a commonly used one-step modality for peritoneal surface malignancies. Despite the gain in popularity and effectiveness, HIPEC is still associated with significant post-operative morbidity and mortality. Liver failure, following HIPEC surgery, which does not involve major liver resection has not been well defined or reported. Hence, we report a case of liver failure in a 51-year-old lady, with recurrent carcinoma ovary, who underwent cytoreductive surgery followed by HIPEC and the potential multifactorial causes that could have caused it.
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spelling pubmed-67167442019-09-06 Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report Kohli, Pavneet Penumadu, Prasanth Subramaniam., Rajkumar Cureus Anesthesiology Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a commonly used one-step modality for peritoneal surface malignancies. Despite the gain in popularity and effectiveness, HIPEC is still associated with significant post-operative morbidity and mortality. Liver failure, following HIPEC surgery, which does not involve major liver resection has not been well defined or reported. Hence, we report a case of liver failure in a 51-year-old lady, with recurrent carcinoma ovary, who underwent cytoreductive surgery followed by HIPEC and the potential multifactorial causes that could have caused it. Cureus 2019-06-28 /pmc/articles/PMC6716744/ /pubmed/31497453 http://dx.doi.org/10.7759/cureus.5026 Text en Copyright © 2019, Kohli et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Kohli, Pavneet
Penumadu, Prasanth
Subramaniam., Rajkumar
Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title_full Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title_fullStr Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title_full_unstemmed Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title_short Acute Liver Failure Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Case Report
title_sort acute liver failure following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a case report
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716744/
https://www.ncbi.nlm.nih.gov/pubmed/31497453
http://dx.doi.org/10.7759/cureus.5026
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AT subramaniamrajkumar acuteliverfailurefollowingcytoreductivesurgeryandhyperthermicintraperitonealchemotherapyacasereport

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