Cargando…

Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation

Chronic atherosclerosis may cause cerebral hypoperfusion and inadequate brain oxygenation, contributing to the progression of cognitive decline. In this study, we exploited two-photon phosphorescence lifetime microscopy to measure the absolute partial pressure of oxygen (PO(2)) in cortical tissue in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Baoqiang, Lu, Xuecong, Moeini, Mohammad, Sakadžić, Sava, Thorin, Eric, Lesage, Frederic
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716780/ https://www.ncbi.nlm.nih.gov/pubmed/31469849 http://dx.doi.org/10.1371/journal.pone.0221547

Ejemplares similares

Impact of atherosclerotic disease on cerebral microvasculature and tissue oxygenation in awake LDLR−/−hApoB+/+ transgenic mice
por: Lu, Yuankang, et al.
Publicado: (2019)

Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation
por: Gagnon, Louis, et al.
Publicado: (2016)

Compromised microvascular oxygen delivery increases brain tissue vulnerability with age
por: Moeini, Mohammad, et al.
Publicado: (2018)

A Pilot Study Investigating Changes in Capillary Hemodynamics and Its Modulation by Exercise in the APP-PS1 Alzheimer Mouse Model
por: Lu, Xuecong, et al.
Publicado: (2019)

More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction
por: Li, Baoqiang, et al.
Publicado: (2019)

Measurement of cerebral microvascular compliance in a model of atherosclerosis with optical coherence tomography
por: Baraghis, E., et al.
Publicado: (2011)

Cerebral tissue pO(2) response to treadmill exercise in awake mice
por: Moeini, Mohammad, et al.
Publicado: (2020)

Cortical microvascular blood flow velocity mapping by combining dynamic light scattering optical coherence tomography and two-photon microscopy
por: Pian, Qi, et al.
Publicado: (2023)

Quantitative cerebral blood flow with Optical Coherence Tomography
por: Srinivasan, Vivek J., et al.
Publicado: (2010)

Large arteriolar component of oxygen delivery implies safe margin of oxygen supply to cerebral tissue
por: Sakadžić, Sava, et al.
Publicado: (2014)

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue
por: Sakadžić, Sava, et al.
Publicado: (2010)

Longitudinal optical coherence tomography imaging of tissue repair and microvasculature regeneration and function after targeted cerebral ischemia
por: Lu, Yuankang, et al.
Publicado: (2020)

Baseline oxygen consumption decreases with cortical depth
por: Mächler, Philipp, et al.
Publicado: (2022)

Rat Pial Microvascular Changes During Cerebral Blood Flow Decrease and Recovery: Effects of Cyanidin Administration
por: Mastantuono, Teresa, et al.
Publicado: (2018)

Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex
por: Hartung, Grant, et al.
Publicado: (2021)

Microvascular cerebral blood flow response to intrathecal nicardipine is associated with delayed cerebral ischemia
por: Sathialingam, Eashani, et al.
Publicado: (2023)

Macrovascular and microvascular cerebral blood flow in adults at risk for Alzheimer's disease
por: Clark, Lindsay R., et al.
Publicado: (2017)

Cerebral metabolism in a mouse model of Alzheimer’s disease characterized by two-photon fluorescence lifetime microscopy of intrinsic NADH
por: Gómez, Carlos A., et al.
Publicado: (2018)

Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis
por: Munting, Leon P, et al.
Publicado: (2021)

Validation of red blood cell flux and velocity estimations based on optical coherence tomography intensity fluctuations
por: Marchand, Paul J., et al.
Publicado: (2020)

Differential reductions in the capillary red-blood-cell flux between retina and brain under chronic global hypoperfusion
por: Li, Baoqiang, et al.
Publicado: (2023)

On the regional distribution of cerebral microvascular ‘raspberries’ and their association with cerebral atherosclerosis and acute circulatory failure
por: Ek Olofsson, Henric, et al.
Publicado: (2023)

Longitudinal decrease in blood oxygenation level dependent response in cerebral amyloid angiopathy
por: Switzer, Aaron R., et al.
Publicado: (2016)

Spatially resolved estimation of metabolic oxygen consumption from optical measurements in cortex
por: Sætra, Marte J., et al.
Publicado: (2020)

Decreased coronary blood flow velocity in two patients with coronary microvascular spasm: case series(†)
por: Takahashi, Hiroshi, et al.
Publicado: (2018)

In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH
por: Yaseen, Mohammad A., et al.
Publicado: (2013)

Due to intravascular multiple sequential scattering, Diffuse Correlation Spectroscopy of tissue primarily measures relative red blood cell motion within vessels
por: Carp, Stefan A., et al.
Publicado: (2011)

Cerebral blood flow pulsatility and cerebral artery stiffness acutely decrease during hemodialysis
por: Paré, Mathilde, et al.
Publicado: (2023)

Characterization of the microvascular cerebral blood flow response to obstructive apneic events during night sleep
por: Zirak, Peyman, et al.
Publicado: (2018)

Effects of arterial blood gas levels on cerebral blood flow and oxygen transport
por: Payne, S. J., et al.
Publicado: (2011)

Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease
por: Korte, Nils, et al.
Publicado: (2020)

Decreased Relative Cerebral Blood Flow in Unmedicated Heroin-Dependent Individuals
por: Yang, Wenhan, et al.
Publicado: (2020)

Cutaneous Microvascular Blood Flow and Reactivity in Hypoxia
por: Treml, Benedikt, et al.
Publicado: (2018)

A Novel Method of Combining Blood Oxygenation and Blood Flow Sensitive Magnetic Resonance Imaging Techniques to Measure the Cerebral Blood Flow and Oxygen Metabolism Responses to an Unknown Neural Stimulus
por: Simon, Aaron B., et al.
Publicado: (2013)

Short‐term external counterpulsation augments cerebral blood flow and tissue oxygenation in chronic cerebrovascular occlusive disease
por: Buschmann, E. E., et al.
Publicado: (2018)

An investigation of cerebral oxygen utilization, blood flow and cognition in healthy aging
por: Catchlove, Sarah J., et al.
Publicado: (2018)

Regulation of Cerebral Blood Flow
por: Peterson, Eric C., et al.
Publicado: (2011)

Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation
por: Shin, Paul, et al.
Publicado: (2023)

Delayed recovery of cerebral oxygenation and cerebral blood flow after profound hypothermic circulatory arrest
por: Voqt, S, et al.
Publicado: (2000)

Changes in cerebral oxygen saturation and cerebral blood flow velocity under mild +Gz hypergravity
por: Konishi, Toru, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ljsoef6h9lo94vs0lmg0k3nh5q