Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways

BACKGROUND: Apixaban effectively lowers the risk of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation. Systemic exposure to a given apixaban dose depends on multiple clearance pathways. Though routine quantification of direct oral anticoagulants (DOACs) in neuro...

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Detalles Bibliográficos
Autores principales: Huppertz, Andrea, Grond-Ginsbach, Caspar, Dumschat, Chris, Foerster, Kathrin I., Burhenne, Jürgen, Weiss, Johanna, Czock, David, Purrucker, Jan C., Rizos, Timolaos, Haefeli, Walter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716843/
https://www.ncbi.nlm.nih.gov/pubmed/31464657
http://dx.doi.org/10.1186/s40360-019-0331-9

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