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HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya

BACKGROUND: HIV infection is associated with more frequent and severe episodes of malaria and may be the result of altered malaria-specific B cell responses. However, it is poorly understood how HIV and the associated lymphopenia and immune activation affect malaria-specific antibody responses. METH...

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Detalles Bibliográficos
Autores principales: Odhiambo, Eliud O., Datta, Dibyadyuti, Guyah, Bernard, Ayodo, George, Ondigo, Bartholomew N., Abong’o, Benard O., John, Chandy C., Frosch, Anne E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716850/
https://www.ncbi.nlm.nih.gov/pubmed/31470903
http://dx.doi.org/10.1186/s12936-019-2915-7