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The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients
BACKGROUND: BRAF mutations occur in 2–4% non-small cell lung cancer (NSCLC) patients and can be categorized into three functional classes based on signaling mechanism and kinase activity: RAS-independent kinase-activating V600 monomers (class 1), RAS-independent kinase-activating dimers (class 2) an...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716889/ https://www.ncbi.nlm.nih.gov/pubmed/31470866 http://dx.doi.org/10.1186/s12967-019-2036-7 |