The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients

BACKGROUND: BRAF mutations occur in 2–4% non-small cell lung cancer (NSCLC) patients and can be categorized into three functional classes based on signaling mechanism and kinase activity: RAS-independent kinase-activating V600 monomers (class 1), RAS-independent kinase-activating dimers (class 2) an...

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Detalles Bibliográficos
Autores principales: Lin, Quan, Zhang, Haoran, Ding, Huaxin, Qian, Jun, Lizaso, Analyn, Lin, Jing, Han-Zhang, Han, Xiang, Jianxing, Li, Yuping, Zhu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716889/
https://www.ncbi.nlm.nih.gov/pubmed/31470866
http://dx.doi.org/10.1186/s12967-019-2036-7

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