Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity analyses

The safety and immunogenicity of the second generation oral enterotoxigenic Escherichia coli (ETEC) vaccine ETVAX, consisting of inactivated recombinant E. coli strains over-expressing the colonization factors (CFs) CFA/I, CS3, CS5 and CS6 and the heat labile toxoid LCTBA, were evaluated in Banglade...

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Detalles Bibliográficos
Autores principales: Akhtar, Marjahan, Chowdhury, Mohiul I., Bhuiyan, Taufiqur R., Kaim, Joanna, Ahmed, Tasnuva, Rafique, Tanzeem A., Khan, Arifuzzaman, Rahman, Sadia I.A., Khanam, Farhana, Begum, Yasmin A., Sharif, Mir Z., Islam, Laila N., Carlin, Nils, Maier, Nicole, Fix, Alan, Wierzba, Thomas F., Walker, Richard I., Bourgeois, A. Louis, Svennerholm, Ann-Mari, Qadri, Firdausi, Lundgren, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717083/
https://www.ncbi.nlm.nih.gov/pubmed/30473185
http://dx.doi.org/10.1016/j.vaccine.2018.11.040

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