The synthesis of branched-chain fatty acids is limited by enzymatic decarboxylation of ethyl- and methylmalonyl-CoA

Most fatty acids (FAs) are straight chains and are synthesized by fatty acid synthase (FASN) using acetyl-CoA and malonyl-CoA units. Yet, FASN is known to be promiscuous as it may use methylmalonyl-CoA instead of malonyl-CoA and thereby introduce methyl-branches. We have recently found that the cyto...

Descripción completa

Detalles Bibliográficos
Autores principales: Dewulf, Joseph P., Gerin, Isabelle, Rider, Mark H., Veiga-da-Cunha, Maria, Van Schaftingen, Emile, Bommer, Guido T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717113/
https://www.ncbi.nlm.nih.gov/pubmed/31416829
http://dx.doi.org/10.1042/BCJ20190500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717113/
https://www.ncbi.nlm.nih.gov/pubmed/31416829
http://dx.doi.org/10.1042/BCJ20190500

Ejemplares similares