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Correlation between the glucose level and the development of acute pancreatitis

OBJECTIVE: To investigate the correlation between the level of glucose in serum and the development of acute pancreatitis (AP). METHODS: Data of 153 AP cases were collected, in which there were 130 patients with mild AP (MAP), 4 with moderate-severe AP (MSAP) and 19 with severe AP (SAP). At the time...

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Autores principales: Sun, Yun-fu, Song, Yu, Liu, Chang-sheng, Geng, Jian-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717129/
https://www.ncbi.nlm.nih.gov/pubmed/31485188
http://dx.doi.org/10.1016/j.sjbs.2018.11.012
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author Sun, Yun-fu
Song, Yu
Liu, Chang-sheng
Geng, Jian-li
author_facet Sun, Yun-fu
Song, Yu
Liu, Chang-sheng
Geng, Jian-li
author_sort Sun, Yun-fu
collection PubMed
description OBJECTIVE: To investigate the correlation between the level of glucose in serum and the development of acute pancreatitis (AP). METHODS: Data of 153 AP cases were collected, in which there were 130 patients with mild AP (MAP), 4 with moderate-severe AP (MSAP) and 19 with severe AP (SAP). At the time of admission, following indexes of patients were recorded: glucose, APACHE II score, TNF-α and C-reaction protein (CRP). RESULTS: At the time of admission, the levels of glucose in serum and APACHE II scores in the MSAP and SAP groups were significantly higher than those in the MAP group, but after treatment, the level of glucose in serum was recovered in 95.8% of the patients in the MAP group, while this digit in the SAP group remained to be 68.4%; in the SAP group, the levels of TNF-α and CRP in patients with sustained hypertension were significantly higher than those with non-persistent hypertension; in terms of the length of stay in hospital, the SAP group was shorter than that in the non-treatment group, and the difference had statistical significance (p < 0.05). Moreover, we found that the level of glucose in serum was positively correlated with the APACHE II scores, TNF-α and CRP. CONCLUSION: Glucose level in serum can be used as one of the indicators for evaluating the severity and development of AP in clinical practice.
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spelling pubmed-67171292019-09-04 Correlation between the glucose level and the development of acute pancreatitis Sun, Yun-fu Song, Yu Liu, Chang-sheng Geng, Jian-li Saudi J Biol Sci Article OBJECTIVE: To investigate the correlation between the level of glucose in serum and the development of acute pancreatitis (AP). METHODS: Data of 153 AP cases were collected, in which there were 130 patients with mild AP (MAP), 4 with moderate-severe AP (MSAP) and 19 with severe AP (SAP). At the time of admission, following indexes of patients were recorded: glucose, APACHE II score, TNF-α and C-reaction protein (CRP). RESULTS: At the time of admission, the levels of glucose in serum and APACHE II scores in the MSAP and SAP groups were significantly higher than those in the MAP group, but after treatment, the level of glucose in serum was recovered in 95.8% of the patients in the MAP group, while this digit in the SAP group remained to be 68.4%; in the SAP group, the levels of TNF-α and CRP in patients with sustained hypertension were significantly higher than those with non-persistent hypertension; in terms of the length of stay in hospital, the SAP group was shorter than that in the non-treatment group, and the difference had statistical significance (p < 0.05). Moreover, we found that the level of glucose in serum was positively correlated with the APACHE II scores, TNF-α and CRP. CONCLUSION: Glucose level in serum can be used as one of the indicators for evaluating the severity and development of AP in clinical practice. Elsevier 2019-02 2018-11-22 /pmc/articles/PMC6717129/ /pubmed/31485188 http://dx.doi.org/10.1016/j.sjbs.2018.11.012 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Sun, Yun-fu
Song, Yu
Liu, Chang-sheng
Geng, Jian-li
Correlation between the glucose level and the development of acute pancreatitis
title Correlation between the glucose level and the development of acute pancreatitis
title_full Correlation between the glucose level and the development of acute pancreatitis
title_fullStr Correlation between the glucose level and the development of acute pancreatitis
title_full_unstemmed Correlation between the glucose level and the development of acute pancreatitis
title_short Correlation between the glucose level and the development of acute pancreatitis
title_sort correlation between the glucose level and the development of acute pancreatitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717129/
https://www.ncbi.nlm.nih.gov/pubmed/31485188
http://dx.doi.org/10.1016/j.sjbs.2018.11.012
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