All trans-retinoic acid protects against acute ischemic stroke by modulating neutrophil functions through STAT1 signaling

BACKGROUND AND PURPOSE: Regulation of neural inflammation is considered as a vital therapeutic target in ischemic stroke. All-trans retinoic acid (atRA), a potent immune modulator, has raised interest in the field of stroke therapy. However, the immunological mechanisms for atRA-mediated neuroprotec...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Wang, Julie, Hu, Mengyan, Chen, Xiao, Lu, Zhengqi, Bellanti, Joseph A., Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717357/
https://www.ncbi.nlm.nih.gov/pubmed/31472680
http://dx.doi.org/10.1186/s12974-019-1557-6

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